Where to store floxal eye drops. Phloxal. Composition, dosage form, mechanism of action. Indications and contraindications for use. Instructions for use. Side effects, prices and reviews. Instructions for use for the treatment of children

I got keratitis when I got eyelash extensions. The next day after the procedure, the right eye ached, it became red, it was painful to look at the light. I went to an ophthalmologist who prescribed Floxal. Eyelashes, of course, had to be removed. The course of treatment lasted a week. Girls, I want to warn you: do not save money and do beauty procedures from trusted masters in ... I got keratitis when I got eyelash extensions. The next day after the procedure, the right eye ached, it became red, it was painful to look at the light. I went to an ophthalmologist who prescribed Floxal. Eyelashes, of course, had to be removed. The course of treatment lasted a week. Girls, I want to warn you: do not save money and do beauty procedures with proven masters in the salon, and do not be fooled by cheapness. Moreover, these are the eyes ... It turns out that I got a bacterial infection.

A few months ago I had a very large stye, they opened it for me in the hospital. I regret that I didn’t treat it, I hoped that it would go away on its own. Brought to this state. After the operation, the doctor advised me to start smearing with Floxal ointment at the slightest sign of barley. Just a week ago I felt that it was starting again. I went straight to the pharmacy... A few months ago I had a very large stye, they opened it for me in the hospital. I regret that I didn’t treat it, I hoped that it would go away on its own. Brought to this state. After the operation, the doctor advised me to start smearing with Floxal ointment at the slightest sign of barley. Just a week ago I felt that it was starting again. I immediately ran to the pharmacy, bought Floksal and smeared it. Barley did not even have time to develop, it immediately began to decline. I smeared my eyes for five days. Good product, really helps!

I had a minor operation on the lacrimal duct, it is not very serious, but after it I was still prescribed an antibiotic to prevent complications. The pharmacy advised to take it in the form of Floxal ointment. I listened to the supervisor. The ointment was applied without any problems at all, just laid behind the eyelid. Absolutely no discomfort when applied -... I had a minor operation on the lacrimal duct, it is not very serious, but after it I was still prescribed an antibiotic to prevent complications. The pharmacy advised to take it in the form of Floxal ointment. I listened to the supervisor. The ointment was applied without any problems at all, just laid behind the eyelid. Absolutely no discomfort when applied - no burning, no pain, like drops! There were no side effects during the use either. In general, I am satisfied with the ointment, I recovered quickly after the operation.

He treated barley with ointment Floksal. Helped quickly and painlessly) Therefore, I decided to share with you, maybe my review will be useful to someone! Barley was for the first time in my life, a year ago. We went to the river to rest, there was a strong wind, apparently the eye was puffed out, and after a few days a bump on the eye began to grow. There was a lot of itching... He treated barley with ointment Floksal. Helped quickly and painlessly) Therefore, I decided to share with you, maybe my review will be useful to someone! Barley was for the first time in my life, a year ago. We went to the river to rest, there was a strong wind, apparently the eye was puffed out, and after a few days a bump on the eye began to grow. There was intense itching and pain. Floksal was advised to me in a pharmacy when I came to them for medicine. For the price, it is inexpensive. Been on for a week or so. The effect of it was fast, everything went without a trace!

Victoria

At the beginning of summer, my son and I went to the seaside, and literally a couple of days later my eyes began to itch. I thought conjunctivitis was due to acclimatization, I just washed my eyes with water for a couple of days, but in the end it turned out to be barley. At the nearest pharmacy, the pharmacist advised Floxal ointment, at a price of just over 100 rubles, a tube for sure ... At the beginning of summer, my son and I went to the seaside, and literally a couple of days later my eyes began to itch. I thought conjunctivitis was due to acclimatization, I just washed my eyes with water for a couple of days, but in the end it turned out to be barley. In the nearest pharmacy, the pharmacist advised the Floxal ointment, at a price of only a little more than 100 rubles, the tube will definitely last for a long time, I decided to try it. According to the instructions, it should be applied 2-3 times a day for the eyelid of the diseased eye, and I did just that. I personally didn't have any side effects. At the first application, I did not notice any special improvements, but by the end of the evening my eyes stopped abscessing and itching. In the morning I already noticed that the swelling and redness began to subside, and after a few days there was no trace of barley at all. The ointment really helped, you can say it saved my vacation, so now I trust only her!

I had such an unpleasant condition as blepharitis. I don’t even know where I picked it up, it didn’t seem to foretell anything. This is when the eyelids around the edges turn red and become very inflamed. It felt very unpleasant, but the main thing was that I could not work at the computer. The pharmacy advised me the antibiotic Floxal, in the form of an ointment .... I had such an unpleasant condition as blepharitis. I don’t even know where I picked it up, it didn’t seem to foretell anything. This is when the eyelids around the edges turn red and become very inflamed. It felt very unpleasant, but the main thing was that I could not work at the computer. The pharmacy advised me the antibiotic Floxal, in the form of an ointment. I bought a small tube and applied it to both eyes the same evening. It stinged a little after application, but it went away almost immediately. It got easier after a few days. The ointment helped a lot!

He treated barley with this ointment. For the first time in my entire adult life, I encountered this muck, although my mother says that she often suffered in childhood. I decided not to go to the doctor, went to the nearest pharmacy, and asked the pharmacist how to help me, they advised me antibiotic drops or ointment. I chose Floksal ointment, I decided ... He treated barley with this ointment. For the first time in my entire adult life, I encountered this muck, although my mother says that she often suffered in childhood. I decided not to go to the doctor, went to the nearest pharmacy, and asked the pharmacist how to help me, they advised me antibiotic drops or ointment. I chose Floksal ointment, I decided that it was more reliable)) And I was not mistaken! The barley began to leave the very next evening, after I started using it. When applied, it does not bake, it is easy to smear yourself. In general, the ointment helped a lot!

I had a strong barley, about a week my eyes were swollen, reddened, the bump was getting bigger. She herself could not cope with folk methods, she had to go to the doctor. Yes, it's good that you went. I was prescribed Floxal ointment there, from which improvement began the very next day. The swelling subsided, and the pain went away. stopped itching. Well... I had a strong barley, about a week my eyes were swollen, reddened, the bump was getting bigger. She herself could not cope with folk methods, she had to go to the doctor. Yes, it's good that you went. I was prescribed Floxal ointment there, from which improvement began the very next day. The swelling subsided, and the pain went away. stopped itching. Well, a week later there was no trace of barley! I am glad that I went to the doctor, otherwise I would have suffered with this traditional medicine! My advice to you, treat serious diseases with medicines!

After the operation, I developed a complication, inflammation, apparently some kind of infection. I went to the doctor and was immediately prescribed an antibiotic for 14 days. It was necessary in the form of an ointment, because it has a wider spectrum of action. I bought Floksal in a pharmacy, I started applying it on the same day. Unpleasant symptoms and swelling passed quickly, redness ... After the operation, I developed a complication, inflammation, apparently some kind of infection. I went to the doctor and was immediately prescribed an antibiotic for 14 days. It was necessary in the form of an ointment, because it has a wider spectrum of action. I bought Floksal in a pharmacy, I started applying it on the same day. Unpleasant symptoms and swelling passed quickly, the redness lasted for another four days, but then it also disappeared. The ointment is effective and does its job. She helped me well, otherwise after the operation there were not enough serious complications!

Marina

A good ointment Floksal, which is already helping me out for the second time. The ointment was prescribed to me by a doctor in the spring and since then the ointment has been in my medicine cabinet, as they say, just in case. The first time I was fishing, but this time I slept with the window open. I put ointment on the bottom... A good ointment Floksal, which is already helping me out for the second time. The ointment was prescribed to me by a doctor in the spring and since then the ointment has been in my medicine cabinet, as they say, just in case. The first time I was fishing, but this time I slept with the window open. I laid the ointment for the lower eyelid, and this will not be difficult. The ointment does not have a characteristic odor and is not very liquid, and therefore does not spread. At the first symptoms, I applied the ointment for three days, and applied the ointment in the daytime. In three days, everything went away, and this is because I did not pull and immediately began to apply the ointment. Some need to be treated for 5 to 7 days. The main thing is not to wait until the barley itself passes, but to start applying the ointment.

I had an eye injury, very small fragments got into my eye. I went to the eye department, they removed me from there using a microscope. After the operation, the doctor prescribed anti-inflammatory treatment - Floxal ointment and moisturizing drops. They let me go home, I bought an ointment, applied it as soon as I arrived. I woke up the next day and it was... I had an eye injury, very small fragments got into my eye. I went to the eye department, they removed me from there using a microscope. After the operation, the doctor prescribed anti-inflammatory treatment - Floxal ointment and moisturizing drops. They let me go home, I bought an ointment, applied it as soon as I arrived. The next day I woke up, it was already noticeably better - severe swelling, redness had gone, I could calmly look at the light. She was treated, as the doctor said - five days, everything is in order!

Barley jumped out and I went to the doctor. The doctor said that the barley could jump out for many reasons - weak immunity, rubbed her eyes with dirty hands or a towel, or slipped through. I was not as interested in the cause of barley as much as in the treatment. I have a conference in a week and I just couldn't... Barley jumped out and I went to the doctor. The doctor said that the barley could jump out for many reasons - weak immunity, rubbed her eyes with dirty hands or a towel, or slipped through. I was not as interested in the cause of barley as much as in the treatment. I have to have a conference in a week and I just could not go out to people in this form. I asked the doctor to prescribe the most effective remedy and he prescribed Floxal ointment. Ointment bought in a pharmacy at the hospital. I don’t remember how much I paid for the ointment, but I remember that it is inexpensive. Improvement from the ointment came on the third day. There were no side effects. Within a week the barley was gone.

I would never have thought that barley is such a serious disease (A month ago, a bump on my upper eyelid began to develop, I thought it would go away on its own, but it didn’t happen there (The bump increased and began to suppurate, the area where the barley was very sore. The general condition was poor - weakness, nausea, no appetite, went to... I would never have thought that barley is such a serious disease (A month ago, a bump on my upper eyelid began to develop, I thought it would go away on its own, but it didn’t happen there (The bump increased and began to suppurate, the area where the barley was very sore. The general condition was poor - Weakness, nausea, no appetite. There were no discomfort or side effects.

Floxal eye drops (international non-proprietary name - Ofloxacin) is a broad-spectrum antimicrobial drug that is used in the local treatment of ophthalmic diseases.

By the breadth of the spectrum of antimicrobial action, as well as by indications for use, ofloxacin is close to antibiotics, but unlike them, it is not a product of natural origin. Ofloxacin is widely used in medicine as an antibacterial agent.

Usually, Floxal is used during local therapy, instilling one drop into the sore eye. The frequency of application of drops is from 2 to 4 times a day. The medicine must be instilled into the region of the lower conjunctival sac. The course of treatment should not exceed two weeks.

Clinical and pharmacological group

Antibacterial drug of the fluoroquinolone group for topical use in ophthalmology.

Terms of sale from pharmacies

Can buy without a doctor's prescription.

Price

How much do Floksal drops cost in pharmacies? The average price is at the level of 186 rubles.

Composition and form of release

Floksal is produced in two dosage forms:

Eye drops: transparent light yellow solution (5 ml in dropper bottles, 1 bottle in a cardboard box);
Eye ointment: light yellow, homogeneous (3 g in tubes, 1 tube in a cardboard box).

The composition of 1 ml of eye drops includes:

Auxiliary components: sodium chloride - 9 mg; benzalkonium chloride - 0.025 mg; sodium hydroxide (1M solution) - 2.5-3.5 mg; hydrochloric acid (1M solution) - 4.5-5.5 mg; water for injection - up to 1 ml.

The composition of 1000 mg eye ointment includes:

Active substance: ofloxacin - 3 mg;
Auxiliary components: wool fat - 50 mg; liquid paraffin - 100 mg; white petroleum jelly - 847 mg.

Pharmacological effect

Floksal is a broad-spectrum antimicrobial drug from the group of fluoroquinolones. The bactericidal action of ofloxacin is associated with the blockade of the enzyme DNA gyrase in bacterial cells.

Highly active against most gram-negative microorganisms: Esherichia coli, Salmonella spp., Proteus spp., Morganella morganii, Shigella spp., Klebsiella spp., Enterobacter spp., Serratia spp., Citrobacter spp., Yersinia spp., Providencia spp., Haemophilus influenzae, Neisseria gonorrhoeae, Neisseria meningitidis, Mycoplasma spp., Legionella pneumophila, Acinetobacter spp., Chlamydia spp.

Floksal is active against some gram-positive microorganisms, in particular Staphylococcus spp., Streptococcus spp.

Anaerobic bacteria (except Bacteroides urealyticus) are insensitive to the drug.

Microorganisms producing β-lactamase are sensitive to ofloxacin.

Moderately sensitive to ofloxacin Enterococcus faecalis, Streptococcus pneumoniae, Pseudomonas spp.

Indications for use

Indications for the appointment of Floxal are infectious and inflammatory pathologies of the anterior part of the eye, provoked by microorganisms sensitive to ofloxacin:

Dacryocystitis.
Blepharitis.
Chlamydial eye infection, ulcer and corneal keratitis.

Also, the drug is used to treat and prevent bacterial infection after surgery and eye injuries.

Contraindications

Drops have only a few contraindications:

Individual intolerance to any of the components of the drops or ointment.
Pregnancy and lactation (there is not enough research on the use of Floxal during pregnancy and lactation).

Appointment during pregnancy and lactation

The state of pregnancy and lactation is a contraindication for the use of Floxal eye drops. The use of the drug is possible only in cases where the expected therapeutic effect exceeds the potential risk to the formation of the child's body.

Dosage and method of application

As indicated in the instructions for use, Floxal in the form of eye drops is prescribed 1 drop in the lower conjunctival sac of the affected eye 2-4 times / day. It is not recommended to use the drug for more than 2 weeks.

If it is necessary to use more than one drug simultaneously, the minimum interval between instillations of 5 minutes should be observed.

When using the drug in the form of an eye ointment, 1.5 cm strips of ointment are placed behind the lower eyelid of the affected eye 2-3 times / day; in the case of chlamydial infection - 5 times / day. It is not recommended to use the drug for more than 2 weeks.

Perhaps a combination of eye drops and ointment Floksal.

With the simultaneous use of more than one drug, the ointment should be used last.

Adverse reactions

Floksal is well tolerated by patients. Side effects occur in individuals with increased individual sensitivity to the components of the drops and are expressed by the following clinical symptoms:

blurred vision, which is of a short-term nature;
rashes around the eyelids;
lacrimation;
burning in the eyes;
redness of the mucous membranes of the eyes;
swelling of the eyelids;
sensation of a foreign body in the eyes;
increased sensitivity to light.

If side effects occur, the patient should consult a doctor.

Overdose

There were no reports of cases of overdose. Therapy is symptomatic, you need to quickly rinse the eye with clean water.

special instructions

Sunglasses should be worn (due to the possible development of photophobia) and prolonged exposure to bright light should be avoided.

After applying the ointment, visual acuity temporarily worsens, which must be taken into account when driving a car and working with mechanisms.

Compatibility with other drugs

The drug interaction of the drug Floksal is not described.

Floksal for children - antibacterial drops, in the treatment of conjunctivitis provide a quick and lasting therapeutic effect. The active substance is ofloxacin from the group of fluoroquinols, the action is to disrupt the processes of DNA synthesis in pathogens. It has a detrimental effect on bacteria that are not affected by other antibiotics and sulfa drugs - staphylococci, streptococci, E. coli, Klebsiella, enterococci and others.

Floksal in the form of drops acts 10 minutes after application, is characterized by a long therapeutic effect for 4-6 hours.

It is allowed to use Floksal as a prophylactic. The drug begins to act even before the first signs of conjunctivitis appear and continues to prevent the development of infection for several hours if the instructions for use are followed.

Produced by a pharmaceutical company in the form of eye drops and as an eye ointment. Mostly eye drops are used because they are more rational. Since Floksal does not have systemic side effects and does not cause irritation of the mucous membrane of the eyes, it is used from the first hours of a newborn's life.

It is used for infectious diseases of the anterior chamber of the eyes, which are caused by microorganisms susceptible to ofloxacin:

Acute purulent inflammation of the hair follicle of the eyelash or sebaceous gland ();
Conjunctivitis;
inflammation of the cornea of the eye;
Infection in the eye caused by chlamydia;
Corneal ulcer caused by bacteria.

Instructions for use

Detailed instructions on how to use the drug (dose of the drug, in what form and duration of treatment) are given by the attending physician. The dosage is calculated depending on the age and severity of the disease.

Before using the antibiotic Floksal, the presence of pathogenic microorganisms sensitive to it is detected, then the treatment will be more effective.

Before you start dripping drops into your eyes, you should wash your hands. The bottle is shaken and opened. After that, the lower eyelid is gently pulled down, and, pressing the vial, 1 drop is injected into the conjunctival sac.

If no other treatment is prescribed, Floxal drops are used for children and newborns, one drop every 6 hours. The course of treatment is not more than two weeks.

If ointment is applied, hands should also be washed before use. Then the lower eyelid is carefully pulled down, and slowly pressing the tube, the ointment is injected into the conjunctival sac in the right amount. Then, to evenly distribute the drug, you need to close your eye and gently press the eyeball in a circular motion.

If no other treatment is prescribed, then the ointment is injected 1 cm into the conjunctival sac every 8 hours. If chlamydia is detected, the ointment is administered every 4 to 6 hours.

There are many positive reviews about the effectiveness of Floxal drops for conjunctivitis in children under one year old. Instructions for use of this drug includes some rules. It is important to drip into both eyes at once. It is necessary to follow the recommendations of the pediatrician. Sometimes the following scheme is used: on the first day, the child is dripped into the eyes every 4 hours, then every 6 hours. The duration of treatment is 5 - 7 days.

But many parents neglect this rule and stop treatment as soon as the child gets better. It is categorically impossible to do this, because if pathogenic microorganisms do not die, then they develop resistance to ofloxacin. Then you have to resort to the use of drugs with a stronger antibiotic, which is difficult for the child.

Phloxal with dacryocystitis

Since the beginning of 2000, neonatal dacryocystitis has been common, which develops when used to prevent gonoblenorrhea. At the same time, the ointment base clogs the lacrimal ducts, disrupts their patency, in addition to the gelatinous plug.

As a result of parents' untimely appeal to doctors, late diagnosis and irrational use of antibacterial drugs for the prevention and treatment of dacryocystitis, phlegmon of the lacrimal sac may develop as a complication.

Currently, staff of maternity hospitals and pediatricians are being trained on the prevention and treatment of neonatal dacryocystitis. Liquid forms of topical antibiotics are recommended for use. The most effective and convenient are Floxal eye drops, the ointment is prescribed less frequently.

The pharmaceutical industry offers a large number of antibacterial drugs for topical use in ophthalmology, but many of them cannot be used to treat children under one year old.

Some of them are toxic to the child's body, and most drugs cause irritation of the conjunctiva. Floksal eye drops are not only effective for prevention and therapy, but are also available in a form that is convenient for use, while not causing discomfort and pain when used as indicated by the instructions.

If there is no improvement within 2 days, then the pediatrician selects other eye drops and appropriate instructions for use are given. Similar agents for the active substance include Uniflox and Dancil, and drops such as, and other cheaper analogues are known by the mechanism of action. The price of drops in Russia ranges from 177 to 230 rubles.

Among the antibacterial drugs of the fluoroquinoline group, Floxal is distinguished by its average price and high efficiency. However, pharmacies dispense it by prescription. And it's justified.

Floxal eye drops are a drug that quickly relieves symptoms and treats purulent inflammation of the eye. But it should not be used recklessly.

Phloxal - light, weak yellow, transparent drops. In plastic dropper bottles of 5 mg. Bottles are best used individually.

As part of the antibacterial drug of the fluoroquinoline group ofloxacin (in 1 ml of its 3 mg). As well as benzalkonium and sodium chlorides, sodium hydrochloride, hydrochloric acid, purified water.

Ofloxacin has the ability to replace DNA gylase enzymes in bacterial cells, and this leads to their stabilization and, in the future, to death.

The high efficiency of Floksal is due to a wide spectrum of action.

The drug is active against all microorganisms that produce β-lactase. And these are almost all known gram-negative and some gram-positive (Staphylococcus spp., Streptococcus spp) microbes. The exception is anaerobic bacteria that are resistant to ofloxacin.

The effect of the application occurs after 10-15 minutes and lasts at least 10 hours. After topical application, Ofloxacin penetrates into all structures of the eye and is absorbed into the systemic circulation (in small quantities). It has been found in breast milk during research.

However, no cases of Floxal poisoning have been recorded. Since the drug enters the body in very small doses, harmless to humans.

Ophthalmologists prescribe these eye drops in cases where it is not possible to conduct a study of the pathogenic flora.

Floksal and its analogues (Dancil and Uniflox) have another important quality, according to the instructions for use, they can be used from infancy (for newborns). They have a limited number of prohibitions to use.

There will be two reasons for use: prevention of infection of an injured or operated eye, infection of the external components of the eye.

Since it is prescribed as a prophylactic:

with eye injuries, wounds, foreign bodies with a violation of the integrity of the structures of the eye;
after ophthalmic operations, to prevent infection of the eye.

As a cure for infection, Floxal (its analogues) is effective:

with blepharitis (inflammatory processes on the edges of the eyelashes);
with conjunctivitis (inflammatory processes of the mucous membrane of the eye);
with hordeoliums (barley or purulent inflammation in the sebaceous glands of Zeiss);
with purulent chalazion, (chronic blockage of the sebaceous glands);
with dacryocystitis (purulent inflammation of the lacrimal sac);
with keratitis (inflammation of the cornea) and more complex corneal ulcers;
as well as chlamydial infections of the eye.

As you can see, Floxal (its analogues) is used to treat infections of the external components of the eye. It is used for topical application and is not injected into internal structures.

The simultaneous use of eye drops and ointment is effective. So, it is recommended to drip drops during the day, and it is better to lay the ointment at night.

Instructions for use among the possible side effects calls the following:

severe itching and burning sensation in the eye;
rashes, redness of the skin around the eye of an allergic nature;
other allergic manifestations;
photophobia;
profuse lacrimation;
short-term swelling of the eyelids and other external components of the eye.

Contraindications according to the instructions for use include the following factors:

allergies to ofloxacin and other components of eye drops;
pregnancy;
breastfeeding period.

The use of Floksal in pediatrics is widely known. It is prescribed by ophthalmologists for the smallest newborn babies, if necessary, the treatment of complex purulent eye diseases (blennorrhea). It is also indicated for older children for the treatment of purulent infections of the eyes. Ofloxacin has been proven to be fast acting and highly effective in the treatment of children. However, the medicine should be dripped to children only after consulting a doctor. And strictly in the prescribed doses.

Floksal eye drops are dispensed by pharmacies by prescription. The use of the drug must be preceded by a consultation with an ophthalmologist.

Drop drops at least 2 times a day. The maximum number of instillations is 4 times, 2 drops in each eye. In diseases caused by chlamydial infections, an increase of up to 5 times a day is allowed.

The procedure should be carried out in proper sanitary conditions, after washing your hands well with soap and water.

Features of instillation.

Before the procedure, hold the bottle in your hand to warm up the medicine. This will make the procedure more comfortable.
If pus has collected in the eye, it must be washed off with an antiseptic (furatsilin solution) using a cotton swab or cotton swabs, sponge.
A separate sponge (stick) is used for each eye.
Then again you need to wash your hands with soap.
The dropper tip should not touch the eye or other surfaces.
For infections, first drip into the eye, which is less affected (sick).
With preventive measures - only the affected eye (or on the recommendation of a doctor).
Eye drops drip into the pocket under the lower eyelid, slightly pulling it.
Then you should lightly press on the inner edge of the eye and sit with your eye closed for 1-2 minutes.
Then blink frequently.
Simultaneous instillation and use of the ointment is allowed. Here, first they drip, and then after 5-6 minutes they lay the ointment.
If you need to drip another medicine, then this should be done no earlier than 5 minutes after the procedure.
The procedure for instillation in newborns and for children is the same.
An open vial can be stored for up to 6 weeks at room temperature, but not above +25.

The topical application of these eye drops may have a number of features that should be considered when treating with Floxal. So, among the aspects that should be considered when treating with ofloxacin, there will be:

the use of ofloxacin may cause temporary impairment of visual acuity. Unpleasant symptoms disappear within 20–35 minutes. This should be taken into account if there is a need to drive a car or work with complex mechanisms;
contact lenses should be removed during treatment. They can be worn after the completion of the course;
one of the side effects when instilling ofloxacin will be photophobia. To avoid this unpleasant phenomenon, you should wear sunglasses.
when using two or more types of eye drops at the same time, it is necessary to make an interval between Floxal and others for at least 5 minutes.
Do not use an antibiotic for more than 2 weeks. This can cause pathogenic fungal growth.

Analogues, as already noted, Floksala will be Dancil (used for eyes and ears) and Uniflox.

Eye drops of the fluoroquinoline group should be attributed to drugs with a similar effect:

neofloxin,
norbaktin,
Normax,
Norflox,
Tsiprolet,
Tsipromed,
cipropane,
ciprofloxacin,
Arflock,
Oftaviks.

There are more than 120 names of these drugs in total.

Among the analogues most often called:

Levomycetin,
Tobrex,
Albucid.

Heal and be healthy!

Clinical and pharmacological group

Antibacterial drug of the fluoroquinolone group for topical use in ophthalmology

Eye drops in the form of a clear solution of light yellow color.

Excipients: benzalkonium chloride - 0.025 mg, sodium chloride - 9 mg, hydrochloric acid (1M solution) - 4.5-5.5 mg, sodium hydroxide (1M solution) - 2.5-3.5 mg, water for injection - up to 1 ml.

5 ml - dropper bottle (1) - packs of cardboard.

Eye ointment homogeneous, light yellow color.

Excipients: liquid paraffin - 100 mg, wool fat - 50 mg, white vaseline - 847 mg.

3 g - tubes (1) - packs of cardboard.

pharmachologic effect

A broad-spectrum antimicrobial drug from the group of fluoroquinolones for topical use in ophthalmology. The bactericidal action of ofloxacin is associated with the blockade of the enzyme DNA gyrase in bacterial cells.

Highly active against most Gram-negative microorganisms: Esherichia coli, Salmonella spp., Proteus spp., Morganella morganii, Shigella spp., Klebsiella spp., Enterobacter spp., Serratia spp., Citrobacter spp., Yersinia spp., Providencia spp., Haemophilus influenzae, Neisseria gonorrhoeae, Neisseria meningitidis, Mycoplasma spp., Legionella pneumophila, Acinetobacter spp., Chlamydia spp.

Active against some Gram-positive microorganisms, in particular Staphylococcus spp., Streptococcus spp.

Moderately sensitive to ofloxacin Enterococcus faecalis, Streptococcus pneumoniae, Pseudomonas spp.

Microorganisms producing β-lactamase are sensitive to ofloxacin.

To the drug insensitive anaerobic bacteria (except Bacteroides urealyticus).

Pharmacokinetics

When applied topically, the therapeutic concentration of the drug in the tissues of the eye is achieved.

Infectious and inflammatory diseases of the anterior part of the eye caused by microorganisms sensitive to ofloxacin:

Blepharitis;

Conjunctivitis;

Dacryocystitis;

Keratitis;

Corneal ulcer;

Chlamydial eye infection.

Prevention and treatment of bacterial infections after eye injuries and surgical interventions.

Contraindications

Pregnancy;

lactation (breastfeeding);

Hypersensitivity to the components of the drug.

Dosage

drug in the form eye drops appoint 1 drop in the lower conjunctival sac of the affected eye 2-4 times / day. It is not recommended to use the drug for more than 2 weeks.

If it is necessary to use more than one drug simultaneously, the minimum interval between instillations of 5 minutes should be observed.

When using the drug in the form eye ointment 1.5 cm strips of ointment are placed behind the lower eyelid of the affected eye 2-3 times / day; when chlamydial infection- 5 times / day. It is not recommended to use the drug for more than 2 weeks.

Perhaps a combination of eye drops and ointment Floksal.

With the simultaneous use of more than one drug, the ointment should be used last.

Side effects

Maybe: allergic reactions, transient hyperemia of the conjunctiva, burning sensation, discomfort in the eyes, itching and dryness of the conjunctiva, photophobia, lacrimation.

Rarely: dizziness.

Overdose

Data on an overdose of the drug Floxal are not available.

The drug interaction of the drug Floksal is not described.

Sunglasses should be worn (due to the possible development of photophobia) and prolonged exposure to bright light should be avoided.

Influence on the ability to drive vehicles and control mechanisms

After applying the ointment, visual acuity temporarily worsens, which must be taken into account when driving a car and working with mechanisms.

Pregnancy and lactation

There are no data on the negative effect of ofloxacin on the fetus, but the drug is contraindicated for use in

pregnancy

and during lactation (breastfeeding).

Terms of dispensing from pharmacies

The drug is dispensed by prescription.

List B. The drug should be stored out of the reach of children, protected from light at a temperature not exceeding 25 ° C. Shelf life - 3 years.

After opening the vial or tube, the drug should be used for no more than 6 weeks.

Eye drops Floksal 0.3% contain in 1 ml ofloxacin- 3 mg. Excipients: benzalkonium chloride, solution hydrochloric acid, sodium chloride, solution sodium hydroxide, water.
Eye ointment Floksal 0.3% in 1 gram contains ofloxacin in the amount of 3 mg. Excipients: liquid paraffin; wool fat; white vaseline.

Release form

Eye drops are a clear, pale yellow solution. 5 ml of such a solution in a polyethylene bottle with a dropper cap, one such bottle in a cardboard box.

Eye ointment is usually homogeneous, pale yellow in color. 3 g of such an ointment in a tube, one such tube in a cardboard box.

The drug has antibacterial action.

Pharmacodynamics

Ofloxacin is fluoroquinolone(derived quinolonic acid), antibacterial drug that has a bactericidal effect.

Spectrum of antibacterial action ofloxacin: facultative anaerobes, obligate anaerobes, aerobes and some other bacteria such as Chlamydia.

The frequency of occurrence of acquired resistance of certain types of microorganisms varies depending on the region and changes over time. Therefore, the main thing for prescribing the correct treatment of infections is the possession of information about local resistance. Possible cross-resistance ofloxacin and other fluoroquinolones.

Most sensitive species:

gram-positive aerobic bacteria Staphylococcus aureus, Bacillus spp.;
Gram-negative aerobic bacteria Acinetobacter lwoffi, Acinetobacter baumannii, Escherichia coli, Haemophilus influenzae, Klebsiella oxytoca, Enterobacter cloacae, Proteus mirabilis, Haemophilus parainfluenzae, Moraxella catarrhalis, Klebsiella pneumoniae, Serratia marcescens.

Species in which the presence of acquired resistance is possible:

gram-positive aerobic bacteria Enterococcus faecalis, Corynebacterium spp., methoxylene-resistant strains of Streptococcus pneumoniae, Staphylococcus aureus, Staphylococcus epidermidis;
Gram-negative aerobic bacteria Stenotrophomonas maltophilia, Pseudomonas aeruginosa.

Species with innate resistance:

Gram-positive aerobic bacteria Enterococcus spp.

Pharmacokinetics

The effectiveness of the drug depends on the ratio of its highest concentration in the tissue and the minimum inhibitory concentration of the pathogen.

With repeated use, the drug accumulates in the vitreous body in therapeutic concentrations. After the administration of the drug 5 times a day with an exposure of 5 minutes, after 1-2 hours the concentration in the intraocular fluid becomes maximum, and for another 5-6 hours it decreases to zero.

The half-life of Floxal from the blood with its regular use is from 3 to 7 hours.

Infectious diseases of the anterior part of the organ of vision caused by microorganisms sensitive to the drug:

corneal ulcer;
barley;
blepharitis;
conjunctivitis;
keratitis;
dacryocystitis;
chlamydial eye damage.

As well as the prevention and treatment of infectious complications after surgical interventions and eye injuries.

Side effects

Severe reactions after regular use ofloxacin develop rarely, most of them are reversible.

Immediately after using the drug, blurred vision may appear, which disappears after a few minutes.

From the side of immunity: conjunctival hyperemia, angioedema, burning sensation in the eye, anaphylactic reactions, swelling of the oropharynx.
From the nervous system: dizziness.
On the part of the eye: discomfort in the eyes, irritation, keratitis, blurred vision, conjunctivitis, photophobia, dry eyes, lacrimation.
On the part of the digestive system: nausea.
On the part of the skin: swelling of the face and periorbital region.

There is evidence that when used locally, very rarely developed Stevens-Johnson syndrome and toxic epidermal necrosis. The causal relationship of such manifestations with ofloxocin not installed.

Floksal eye drops instructions for use prescribed to instill 1 drop per eyelid of the diseased eye 3-4 times a day.

Instructions for ophthalmic ointment Floksal also recommends using the drug conjunctivally. A strip of ointment up to 1.5 cm is placed in the conjunctival sac 2-3 times a day, with chlamydial lesions - 5 times a day. Ointment and eye drops are not recommended for more than 2 weeks.

You can combine eye ointment and Floxal drops. When more than one drug is taken together locally, the ointment should be used last.

There were no reports of cases of overdose. Therapy - symptomatic, you need to quickly rinse the eye with clean water.

Features of the interaction have not been studied.

The drug is sold only by prescription.

Keep away from children. The drug should be stored in a dark place at temperatures up to 25°C. After opening the tube a or vial, the drug can be used for no more than 6 weeks.

If appeared allergic reaction on Floksal, the reception must be stopped.

With long-term use, it is possible to develop bacterial resistance and the appearance of microorganisms insensitive to the drug. If symptoms worsen or there is no clinical improvement, treatment with Floxal should be discontinued and alternative therapy initiated.

During the treatment period, it is forbidden to use hard contact lenses. Therefore, you need to remove such lenses before using the drug and put them on 20 minutes after instillation.

The following analogues of Floksal eye drops are known: Vigamox, Uniflox.

The drug is approved for use in children and newborns.

There is no evidence of a negative effect of the drug on the fetus, however, despite this, it is forbidden to use it for pregnant and lactating women.

In what cases is the drug "Floxal" (eye drops) used? Instructions for this medication, its composition, contraindications and indications for use will be presented below. In addition, from this article you will learn about what pharmacological features this remedy has, and whether it has side effects.

The composition of the drug

What substances does the drug "Floxal" (eye drops) include? Instructions for use of this medication states that 1 ml of this solution contains approximately 3 mg of the active element in the form of ofloxacin. As for additional substances, they include the following: sodium chloride, hydrochloric acid, sodium hydroxide, injection water and benzalkonium chloride.

This medication (0.3%) goes on sale in a volume of 5 ml. The solution is placed in a sterile plastic dropper bottle. At the same time, it is transparent and has a slightly yellowish tint.

Pharmacological properties of drops

What pharmacological properties does the drug "Floxal" (eye drops) have? The instruction to this tool gives an exhaustive answer to the question asked. It is an antimicrobial drug belonging to the group of fluoroquinolones and has a wide spectrum of action. It is intended exclusively for topical use in ophthalmic practice. The bactericidal effect of the active ingredient is associated with the blockade of the DNA gyrase enzyme in (bacterial) cells.

The presented drug is highly active against many gram-negative and only some gram-positive microorganisms. It should also be noted that bacteria producing beta-lactamase are sensitive to this agent. At the same time, anaerobic microorganisms are absolutely insensitive to the drug.

Indications

When is the drug "Floxal" (eye drops) prescribed? The instruction includes the following list of indications for the use of this drug:

barley;
blepharitis;
dacryocystitis;
conjunctivitis;
corneal ulcer;
keratitis;
chlamydial eye infection.

Thus, the drug "Floxal" is prescribed for infectious and inflammatory diseases of the anterior part of the visual organ, which are caused by bacteria sensitive to ofloxacin.

It should also be noted that the mentioned drug is often used for the prevention and treatment of bacterial infections after surgery and eye injuries.

Contraindications

In what cases should you never use the Floxal medication (eye drops)? Instructions, patient reviews say that the presented remedy is not recommended for use only under the following conditions:

Dosage of the drug

In what dose is the drug "Floxal" (eye drops) usually prescribed? Instructions for children will be presented a little later. For adults, this drug is prescribed in the amount of 1 drop 2 to 4 times a day.

With chlamydial lesions, the dosage of the presented medication is recommended to be increased up to 5 times a day. The duration of therapy depends on the type of disease. However, doctors say that using drops for longer than 2 weeks is highly discouraged.

The drug "Floxal" (eye drops): instruction

For newborns, this drug is prescribed with extreme caution. As for adolescents and adults, they can use this medication without much concern.

After prescribing the mentioned medication, it should be instilled into the conjunctival sac of the eye (into the lower one) exactly in the dosage that was prescribed by the doctor.

If different types of drops are used to treat a particular disease, then the interval between their instillation should be at least 5 minutes.

If the patient uses both ointment and drops at the same time, then the first medicine must be applied last.

Caution in the treatment of ophthalmic diseases

Now you know how to use the drug "Floxal" (eye drops). The instruction for children and adults states that it is highly recommended not to wear lenses (contact lenses) while using this medication.

To prevent photophobia, it is necessary to avoid places where there is bright lighting. In the summer, you should wear dark sunglasses.

After the introduction of drops into the eyes, the patient often has a visual impairment. However, after a short period of time, it is restored.

During the period of use of the presented drug, it is recommended to refrain from driving and other vehicles, as well as performing work with dangerous equipment.

Side effects

Can there be negative consequences after using Floxal eye drops? According to the instructions, this drug has side effects. If it is used incorrectly, the patient may experience allergic reactions, as well as dryness and itching of the conjunctiva, burning sensation, transient hyperemia of the conjunctiva, discomfort in the eyes, lacrimation and photophobia. In rare cases, the patient complains of dizziness.

Medication "Floxal" (eye drops): instructions for children, reviews

Especially for children, the presented medication is not produced. Therefore, in pediatric ophthalmology, the same form of release of the drug "Floxal" is used as for adults.

According to experts, such eye drops can be used in relation to young children, as well as newborn babies. But this should be done very carefully and only as prescribed by the doctor.

As a rule, the drug "Floxal" is prescribed for children for the treatment of infectious and inflammatory processes in the anterior sections of the eyes, which were caused by pathogens sensitive to the active substance ofloxacin.

The dose of the drug and the duration of therapy should be determined only by the doctor. However, the use of this drug should not be longer than 2 weeks.

The usual dosage for young children is 1 drop four times a day. If the doctor has prescribed to the child not only a solution, but also an ointment, then it should be laid behind the eyelid last.

During the use of this remedy, the baby may experience the same side effects as in adults. In this case, the drug should be immediately discontinued.

Analogues and price of the drug

Now you know how to use the drug "Floxal" (eye drops) in relation to young children. Instructions, analogues of this medication are presented in this article.

How much does a solution for the treatment of infectious eye diseases cost? The cost of the drug depends on the manufacturer, as well as the margins of pharmacy chains. However, the average price of this medication is about 200 Russian rubles.

What to do if the patient, for one reason or another, could not purchase the mentioned remedy? There are many analogues of this drug. Choosing according to the active substance, you can purchase Dancil or Uniflox eye drops, as well as Ofloxacin eye ointment.

If you are interested in funds similar in mechanism of action, then these include the following medicines: Normax, Tsipromed, Albucid, Tobrex, Oftaquix, Levomycetin and Sulfacyl sodium.

These drugs are inexpensive, and at the same time they have the same healing properties as the original.